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Gordon Research Conference

posted Jun 16, 2014, 4:54 AM by CellChipGroup   [ updated Jun 16, 2014, 6:39 AM ]

Mario Rothbauer presents our work on cellular micropatterning at the Biointerface Science Symposium of the GRC. 

In the current work, we exploit the unique self-assembly properties of  S-layers to create an anisotropic protein nanobiointerface on-chip with spatially-defined cytophilic (adhesive) and cytophobic (repulsive) properties. While microfluidics controls physical parameters such as shear force and flow velocities, our anisotropic protein nanobiointerface regulates the biological aspects of the co-culture method including biocompatibility, biostability and affinity to non-adherent cells.